Research Paper Volume 16, Issue 18 pp 12608—12622

Figure 7. Effects of the ferroptosis-related gene signature on response to ICB. (A) The high-risk patients had a higher MSI level than the low-risk patients based on ssGSEA approach. (B) The risk score was positively correlated with MSI level based on ssGSEA approach. (C) MSI-H patients had a higher risk score level than MSI-L/MSS patients based on UCSCXenaShiny approach. (D) The risk score was positively correlated with MSI level based on UCSCXenaShiny approach. (E) The high-risk group had a higher proportion of stable disease (SD) and progressive disease (PD) than the low-risk group. (F, G) The SD/PD patients had an increased risk score than the CR/PR group. MSI: microsatellite instability; MSS: microsatellite stability, MSI-L: microsatellite instability-low, MSI-H: microsatellite instability-high, SD: stable disease, PD: progressive disease, CR: complete response, PR: partial response. * represents P < 0.05, ** represents P < 0.01, *** represents P < 0.001.