Research Paper Volume 16, Issue 18 pp 12608—12622
Characterization of a ferroptosis-related gene signature predicting survival and immunotherapeutic response in lung adenocarcinoma
Figure 2. Validation of the predictive ability of the ferroptosis-related gene signature. (A–C) A receiver operating characteristic (ROC) curve was performed and area under the curve (AUC) was calculated in the validation set and two external test sets (GSE72094 and GSE8894). (D–F) Survival analysis was performed in the TCGA cohort, the GSE72094 cohort, and the GSE8894, respectively. (G–I) Principal component analysis of genes consisting the prognostic ferroptosis-related signature revealed a distinct expression pattern between the low- and the high-risk groups in dimensionality.