Research Paper Volume 16, Issue 18 pp 12574—12592
Wenshenqianlie capsule improves benign prostatic hyperplasia via its anti-inflammatory and antioxidant effects
Figure 5. Analysis for the effect of WSQL treatment on metabolites in TP-induced BPH mice. OPLS-DA score plots in (A) negative ion mode and (B) positive ion mode for pair-wise comparisons of BPH with the Ctrl and BPH+WSQL groups respectively. Different metabolites in (C) negative ion mode and (D) positive ion mode for pair-wise comparisons of BPH with the Ctrl and BPH+WSQL groups respectively. OPLS-DA VIP > 1, p < 0.05. (E) Heatmap of hierarchical clustering of significantly different metabolites. (F) KEGG enrichment pathway bubble diagram between BPH and BPH+WSQL groups. (G) Association heatmap between metabolic markers and gut microbial markers. ** p < 0.01 and * p < 0.05. n = 3 for (A–G).