Research Paper Volume 16, Issue 18 pp 12574—12592

Figure 4. WSQL treatment altered the abundance and diversity of the gut microbiota in BPH of BALB/c mice. (A) ASV Venn diagram. (B) Alpha diversity according to Chao1, Observed_species, Shannon, Simpson, Faith_pd, Goods_coverage and Pielou_e. (C) Beta diversity according to PCoA analysis of a weighted_unifrac distance matrix. (D) The taxonomic distributions and relative abundance (%) of top 20 gut microbiota from each group at phylum level. (E) Differential metabolic pathways associated with differential gut microbiota between Ctrl and BPH groups and BPH+WSQL and BPH groups. LDA of differential taxa between (F) BPH and Ctrl groups and (G) BPH+WSQL and BPH groups according to the preset value (LDA > 2, p < 0.05). (H) Heatmap of top 20 gut microbiota at genus level. Taxa names are abbreviated as “p”, phylum, “c”, class, “o”, order; “f”, family, and “g”, genus. * p < 0.05 vs. BPH group. n = 3 for (A–H).