Research Paper Volume 16, Issue 17 pp 12312—12334
Identification of a circadian-based prognostic signature predicting cancer-associated fibroblasts infiltration and immunotherapy response in bladder cancer
Figure 2. The circadian rhythm-based subgroups of TCGA-BLCA. (A) The TCGA-BLCA was divided into two circadian rhythm-based subgroups via unsupervised clustering. (B) Kaplan-Meier analysis of the OS of C1 and C2 subgroups. (C) Association of the circadian rhythm-related subgroups with stage and pathological T/M/N stages. (D) The ESTIMATE, stromal, immune score and tumor purity of the two circadian rhythm-related subgroups, *** p < 0.001.