Research Paper Volume 16, Issue 15 pp 11729—11743
Hsa-miR-181a-2-3p inhibits the oncogenicity of colon cancer by directly targeting STING
Figure 4. STING reverses the biological role of miR-181a-2-3p in colon cancer cells. (A) Examination of cell proliferation by CCK-8 assay. (B) Assessment of cell migration ability by Transwell assay. (C) Measurement of cell apoptosis by flow cytometry. (D) Detection of cell cycle by flow cytometry. Note: Group I was Ctrl+Ctrl, which meant that NC overexpressing miR-181a-2-3p and NC overexpressing STING were co-transfected at the same time. Group II was miR-181a-2-3p+ Ctrl, which means that overexpression of miR-181a-2-3p and NC overexpressing STING were simultaneously co-transfected. Group III was miR-181a-2-3p+STING, which means that overexpression of miR-181a-2-3p and overexpression of STING plasmid were simultaneously transfected.