Research Paper Volume 16, Issue 16 pp 11776—11795
Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging
Figure 1. Quiescence and TGF-β1-stimulated SECRETOME heat-map and schematic representations of molecular pathways. (A) Heat-maps of differentially-expressed proteins in young and old fibroblasts (n=6) (HeatMapper). (B) Analysis of cellular processes linked to differentially-expressed proteins (GOrilla and Panthere). (C) Representation of signaling pathways and links between differently expressed proteins in quiescence and (D) TGF-β1-treated condition (PathVisio).