Figure 6 — Acyl-CoA thioesterase 13 (ACOT13) attenuates the progression of autosomal dominant polycystic kidney disease in vitro via triggering mitochondrial-related cell apoptosis

Research Paper|Volume 16, Issue 16|pp. 11877–11892

Acyl-CoA thioesterase 13 (ACOT13) attenuates the progression of autosomal dominant polycystic kidney disease in vitro via triggering mitochondrial-related cell apoptosis

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Figure 6.ACOT13 overexpression induced mitochondria damage in WT9-12 cells. WT9-12 cells were transfected with ACOT13 OE plasmids. (A) The ATP concentration in cells were detected using an ELISA kit. (B) JC-1 staining was performed to evaluate the MMP level (the ratio of red/green fluorescence intensity) in WT9-12 cells (magnification, 200×). ***P<0.001 vs. control group.