Acyl-CoA thioesterase 13 (<i>ACOT13</i>) attenuates the progression of autosomal dominant polycystic kidney disease <i>in vitro</i> via triggering mitochondrial-related cell apoptosis

Bin Wang; Qi Yang; Lihe Che; Luyao Sun; Na Du

doi:doi:10.18632/aging.206054

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Research Paper Volume 16, Issue 16 pp 11877—11892

Acyl-CoA thioesterase 13 (ACOT13) attenuates the progression of autosomal dominant polycystic kidney disease in vitro via triggering mitochondrial-related cell apoptosis

Figure 5. ACOT13 overexpression triggered WT9-12 cell cycle arrest and apoptosis. WT9-12 cells were transfected with ACOT13 OE plasmids. (A, B) Cell cycle distribution and (C, D) cell apoptosis were analyzed by the flow cytometry analysis. **P<0.01, ***P<0.001 vs. control group.