Acyl-CoA thioesterase 13 (<i>ACOT13</i>) attenuates the progression of autosomal dominant polycystic kidney disease <i>in vitro</i> via triggering mitochondrial-related cell apoptosis

Bin Wang; Qi Yang; Lihe Che; Luyao Sun; Na Du

doi:doi:10.18632/aging.206054

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Research Paper Volume 16, Issue 16 pp 11877—11892

Acyl-CoA thioesterase 13 (ACOT13) attenuates the progression of autosomal dominant polycystic kidney disease in vitro via triggering mitochondrial-related cell apoptosis

Figure 4. ACOT13 overexpression suppressed WT9-12 cell viability and proliferation. WT9-12 cells were transfected with ACOT13 OE plasmids. Cell viability and proliferation were determined using the (A) CCK-8 and (B, C) EdU staining (magnification, 200×) assays, respectively. ***P<0.001 vs. control group.