Research Paper Volume 16, Issue 15 pp 11683—11728

Pan-cancer analysis of immune checkpoint receptors and ligands in various cells in the tumor immune microenvironment

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Figure 7. Bioinformatics analysis of the distribution of 10 immune check site ligands on tissues and cells. (A) Expression ratios of 10 immune checkpoint ligands in tumors, blood, spleen, lung, muscle, and bone marrow tissues; (B) Bioinformatics analysis of the expression of 10 immune checkpoint ligands in 13 cell subsets showed a heat map of the normalized markers for each cluster, with data representing the entire tumor; (C) Bioinformatics analysis of ligands expression at 10 immune checkpoints, histogram showing high and low expression of each receptor on different cell subsets, and data representing the entire tumor.