Research Paper Volume 16, Issue 15 pp 11683—11728

Pan-cancer analysis of immune checkpoint receptors and ligands in various cells in the tumor immune microenvironment

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Figure 11. A significant correlation between immune checkpoint receptor/ligand expression and pan-cancer prognostic value is dependent on DriverDBv3. Expression of NECTIN2 was associated with overall survival (OS) in ACC (A), LGG (B), and LUAD (C); (D) Correlation between the expression of 20 immune checkpoint receptors/ligands and OS of various tumors, red: positive correlation, P < 0.05, blue: negative correlation, P < 0.05, white: no significant difference, P > 0.05; (E) Correlation between the expression of 20 immune checkpoint receptors/ligands and PFS of various tumors, red: positive correlation, P < 0.05, blue: negative correlation, P < 0.05, white: no significant difference, P > 0.05.