Research Paper Volume 16, Issue 15 pp 11668—11682
Solamargine acts as an antiviral by interacting to MZF1 and targeting the core promoter of the hepatitis B virus gene
Figure 5. Solamargine regulates HBV replication by targeting PGL4.74-HBenIIcp-Ce-Del2 related transcription factors. (A) ENII/BCP and a series of deletion mutants from pGL4.74-HBenIIcp-Ce-del1 to pGL4.74-HBenIIcp-Ce-del10 gene sequence. (B) The deletion of HBenIIcp-Ce-del1 to pGL4.74-HBenIIcp-Ce-del10 gene sequence. (C) The deletion of pGL4.74-HBenIIcp-Ce-del2 DNA sequence and the presence of interacting transcription-related proteins in the sequence.