Research Paper Volume 16, Issue 15 pp 11668—11682
Solamargine acts as an antiviral by interacting to MZF1 and targeting the core promoter of the hepatitis B virus gene
Figure 2. Effect of Solamargine on the relative expression of HBV DNA in cell supernatants. HBV plasmid was transfected into Huh7 cells, and 2 d later Solamargine (5 μM) was added into the cells. Samples were collected after 1 d culture and HBV DNA copy number of supernatant was detected by PCR. All assays were performed in triplicate and results are presented as means ± SD. ***P < 0.001, Student’s t-test.