Research Paper Volume 16, Issue 15 pp 11491—11500
Disease progression in Parkinson’s disease patients with mild cognitive impairment: 5-year longitudinal study from the early Parkinson’s disease longitudinal Singapore (PALS) cohort
Figure 1. Motor progression between PD-MCI and PD-NC. (A) Progression slopes of H&Y score in PD-MCI and PD-NC group were 0.11 vs. 0.06, p=0.03. (B) Progression slopes of UPDRS motor score in PD-MCI and PD-NC group were 3.11 vs. 1.90 p=0.00. (C) Progression slopes of PIGD score in PD-MCI and PD-NC group were 0.45 vs. 0.24, p=0.02. Longitudinal linear mixed model was performed to compare the progression slopes of motor outcomes between PD-MCI and PD-NC group; analysis has been adjusted for age of diagnosis, sex and education year. Abbreviations: H&Y: Modified Hoehn and Yahr staging scale; MDS-UPDRS: Movement Disorder Society-Unified Parkinson’s Disease Rating Scale; PIGD: Postural Instability and Gait Disorder.