Research Paper Volume 16, Issue 15 pp 11591—11605

Genome-wide methylation and gene-expression analyses in thalassemia

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Figure 5. Functional enrichment analysis of DMGs by KEGG. The 20 most significantly enriched biological functions in DMC (A) and DMR (B) using KEGG are illustrated in dot plots. Rich factor refers to the proportion of DMGs belonging to a specific term. Node size (gene number) refers to the number of DMGs within each term and node color indicates the level of significance (−log10 p-value). DMGs mean differentially methylated genes.