Research Paper Volume 16, Issue 14 pp 11446—11459
Effectiveness of vaginal probiotics Lactobacillus crispatus chen-01 in women with high-risk HPV infection: a prospective controlled pilot study
Figure 2. Effects of intravaginal transplantation of L. crispatus chen-01 on the diversity and abundance of vaginal microbiota. (A) Comparison of Shannon and Simpson in the groups of C, H-b, H-f and H-Bb. (B) PCoA analysis among the groups of C, H-b, H-f and H-Bb. (C) Heatmap of species composition between before (H-b) and after (H-Bb) probiotic treatment. The abbreviated descriptions are as follows: C: Healthy people without HPV infection; H-b: Patients of HR HPV before enrollment; H-f: Patients of HR-HPV after treatment with placebo; H-Bb: Patients of HR HPV after treatment with probiotic. *P < 0.05; **P < 0.01.