Research Paper Volume 16, Issue 15 pp 11568—11576

Circular RNA circMRPS35 represses malignant progression in osteosarcoma cells via targeting miR-105-5p/FOXO1

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Figure 2. CircMRPS35 contributes to apoptosis and regulates cell cycle of osteosarcoma cells. (AF) The MG63 and MNNG/HOS cells were treated with circMRPS35 overexpressing plasmid. (AD) The cell apoptosis was analyzed by flow cytometry analysis. (E, F) The cell cycle was determined by flow cytometry analysis. **P < 0.01.