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Figure 1.The overexpression of circMRPS35 inhibits cell proliferation of osteosarcoma in vitro and in vivo. (AD) The MG63 and MNNG/HOS cells were treated with circMRPS35 overexpressing plasmid. (A, B) The expression of circMRPS35 was detected by qPCR. (C, D) The cell viability was measured by CCK-8 assay. (EG) The tumorigenesis analysis was performed in nude mice injected with MG63 cells treated with circMRPS35 overexpressing plasmid. **P < 0.01.
Figure 1 — Circular RNA circMRPS35 represses malignant progression in osteosarcoma cells via targeting miR-105-5p/FOXO1 | Aging