Research Paper Volume 16, Issue 14 pp 11385—11408

Integrating single-cell RNA-seq to identify fibroblast-based molecular subtypes for predicting prognosis and therapeutic response in bladder cancer

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Figure 10. Estimation of the relationship between risk scores and the tumor immune microenvironment. (A) Heat map of cytokine expression in high- and low-score groups. * indicates p<0.05, ** indicates p<0.01, *** indicates p<0.001. (B) Correlations between signature score and HALLMARK pathway. (C) Expression analysis of LAG3, CD274, CTLA-4, PDCD1, and TIGIT between high- and low-risk groups.