Research Paper Volume 16, Issue 15 pp 11553—11567

Figure 2. Assessment of the tumor microenvironment based on the deubiquitinating enzyme-related index. (A, B) GSEA analysis was conducted on patients belonging to the high DUBRI group. (C) Variations in tumor purity, ESTIMATEScore, immunity score, and stroma score observed between high and low DUBRI groups. (D) The CIBERSORT technique is used to evaluate the variations in immune cell populations between individuals classified as either high or low DUBRI group. (E) The ssGSEA method evaluates disparities in immune cells and immunological function across patients categorized into the high/low DUBRI group. (F) The connection between DUBRI and immune cell infiltration was analyzed using XCELL, TIMER, QUANTISEQ, MCPCOUNTER, EPIC, CIBERSORT-ABS, and CIBERSORT software.