Research Paper Volume 16, Issue 14 pp 11339—11358

PART1 facilitates tumorigenesis and inhibits ferroptosis by regulating the miR-490-3p/SLC7A11 axis in hepatocellular carcinoma

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Figure 2. PART1 promotes proliferation and inhibits apoptosis of HCC cells. (A) The relative expression of PART1 was measured by RT-qPCR in HCCLM3 and Huh7 cells transfected with siRNA-PART1.1, -PART1.2, and -PART1.3. (B) CCK-8 assay was conducted to evaluate the proliferation of HCCLM3 and Huh7 cells transfected with siRNA-PART1.1 and -PART1.3. (C, D) The cell cycle and cell apoptosis rate of HCCLM3 and Huh7 cells transfected with siRNA-PART1.1 and -PART1.3 were assessed by flow cytometry analysis. *p < 0.05, **p < 0.01, ***p < 0.001.