Research Paper Volume 16, Issue 14 pp 11289—11317

Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacy

class="figure-viewer-img"

Figure 8. Correlation analysis between BAX expression and the expression degree of immune cells obtained from TCGA. (A) The correlation of BAX expression with six types of immune cells (B cell, CD4+ T cell, CD8+ T cell, neutrophil, macrophage, and myeloid dendritic cell) in pan-cancer. (B) The top three tumors with the highest correlation between the degree of immune infiltration and BAX expression were KIRC, LGG and LIHC via TIMER algorithm. (P < 0.05).