Research Paper Advance Articles
Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacy
Figure 13. Enrichment analysis of BAX-related gene. (A) Analysis of twenty proteins interacting with BAX through STRING database. (B) Protein–protein interaction network of BAX was performed via the STRING database. (C) The heat map of correlation between BAX and the top 5 genes (PRPF31, BBC3, PIH1D1, LIG1 and PRMT1) in TCGA tumors. (D) Correlation of BAX and the top 5 genes in the cancer types of TCGA. (E) Bubble plot for KEGG pathway analysis. (F–H) GO enrichment analysis of the top 100 genes that associated with BAX expression.