Research Paper Volume 16, Issue 13 pp 11062—11071

Sevoflurane impedes neuropathic pain by maintaining endoplasmic reticulum stress and oxidative stress homeostasis through inhibiting the activation of the PLCγ/CaMKII/IP3R signaling pathway

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Figure 6. Sevoflurane could reduce oxidative stress and inflammation. (A) Protein bands of P22, P47, NLRP3, IL-1β and TNF-α in Sham group, Model group and Sevoflurane group, (B) relative protein expressions of P22, P47, NLRP3, IL-1β and TNF-α in Sham group, Model group and Sevoflurane group. Sham group vs. Model group, Model group vs. Sevoflurane group, Control group vs. Sevoflurane group, **P<0.01, N=8.