Research Paper Volume 16, Issue 14 pp 11275—11288
Interference with ANXA8 inhibits the malignant progression of ovarian cancer by suppressing the activation of the Wnt/β-catenin signaling pathway via UCHL5
Figure 8. Interference with ANXA8 inactivated the Wnt/β-catenin signaling pathway through UCHL5 to inhibit tumor growth in OC mice. (A) The weight of the tumor in mice; (B) The volume of the tumor in mice; (C) IHC assay was used to detect the expression of KI67; (D) IHC assay was used to assess the expression of cleaved caspase3; (E) Western blotting was used to detect the expression of ANXA8, UCHL5, β-catenin, c-Myc, and CyclinD1 proteins.