Research Paper Volume 16, Issue 14 pp 11275—11288
Interference with ANXA8 inhibits the malignant progression of ovarian cancer by suppressing the activation of the Wnt/β-catenin signaling pathway via UCHL5
Figure 6. Interference with ANXA8 inhibited the invasion and migration of CAOV3 cells through UCHL5. (A) Wound healing assay was used to detect CAOV3 cell migration ability; (B) Transwell assay was used to detect CAOV3 cell invasion ability; (C) Western blot analysis of the expression of invasion and migration-related proteins TIMP1, TIMP2, and MMP2 in CAOV3 cells. ***P<0.001 vs. control; ##P<0.01, ###P<0.001 vs. shRNA-ANXA8+Ov-NC.