Research Paper Volume 16, Issue 13 pp 10972—10984
Unveiling diabetic nephropathy: a novel diagnostic model through single-cell sequencing and co-expression analysis
Figure 3. Weighted gene co-expression network analysis (WGCNA) in DN. (A) Selection of the optimal soft threshold (power of 14) ensuring data conforms to the power law distribution for network construction. (B, C) Gene clustering into 17 non-gray modules, with the green module showing the highest association with disulfidptosis phenotype (correlation and statistical significance). (D) Positive correlation between gene significance for disulfidptosis and module membership within the green module, indicating relevance to DN pathogenesis.