Figure 7. Clinical significance of the IRRS model in TCGA cohort. (A) The Kaplan–Meier survival analysis of the signature for predicting the OS of patients in TCGA cohort. (B) Time-dependent ROC analysis of the signature for predicting the OS of patients in TCGA cohort. (C) Differences in clinicopathologic features and expression levels of prognostic variables between the low- and high-risk groups. (D) The distribution of the IRRS and the vital status of patients in the TCGA cohort. (E) The subgroup survival analysis according to the age, gender, histologic grade, and tumor stage.