Research Paper Advance Articles

Identification of immunotherapy-related subtypes, characterization of tumor microenvironment infiltration, and development of a prognostic signature in gastric carcinoma

class="figure-viewer-img"

Figure 6. Construction of the IRRS model in the TCGA cohort. (A) Expression heatmap of the DEGs between the two distinct subtypes. (B) GO and KEGG enrichment studies of DEGs between different cluster groups. (C) LASSO coefficient profiles of 3 selected genes in the 10-fold cross-validation. (D) Partial likelihood deviance was revealed by the LASSO regression model in the 10-fold cross-validation. (E) Forest plot of hazard ratios for three selected prognostic variables. (F) The coefficients of the three prognostic variables in the LASSO regression model. (G) Sankey plot displayed the correlations among the cluster subgroups, IRRS and vital status.