Research Paper Volume 16, Issue 12 pp 10636—10656

Comprehensive single-cell and bulk RNA-seq analyses reveal a novel CD8+ T cell-associated prognostic signature in ovarian cancer

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Figure 1. Interrogating the cellular constitution of ovarian cancer at single-cell resolution. (A, B) UMAP plot showing the major cell subpopulations in ovarian cancer. (C) Bubble heatmap showing expression levels of selected signature genes in ovarian cancer. Dot size indicates fraction of expressing cells, colored based on normalized expression levels. (D) Relative proportions of diverse cell types across each sample. (E) Feature plots to further identify various immune cells, based on the expression levels of marker genes.