Research Paper Volume 16, Issue 12 pp 10579—10614
Multi omics analysis of mitophagy subtypes and integration of machine learning for predicting immunotherapy responses in head and neck squamous cell carcinoma
Figure 2. CNV and sequence alteration contribute to abnormal mitophagy genes Levels. (A) CNV strongly correlates to gene expression of mitophagy regulators in pan-cancer using spearman analysis. (B, C) Heterozygous and homozygous amplification/deletion of mitophagy regulators in pan-cancer. Amplification, red; Deletion, blue. (D) The location of CNV of mitophagy regulators on 23 chromosomes. (E) CNV of mitophagy regulators in TCGA-HNSC dataset. CNV loss, blue; CNV gain, red. (F) Mutation frequency of mitophagy regulators in pan-cancer.