Research Paper Volume 16, Issue 13 pp 10841—10859

Characterization of the gut microbiota and fecal metabolome in the osteosarcoma mouse model

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Figure 5. (A) Orthogonal partial least squares discriminant analysis (OPLS-DA) of fecal metabolites between the NCG and OG. (B) Bubble diagram of the top 20 enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. (C) Heatmap of fecal metabolites identified using gas chromatography-mass spectrometry (GC-MS). (D) Heatmap of fecal metabolites identified using liquid chromatography-mass spectrometry (LC-MS). (E) Volcano map displaying differential fecal metabolites identified using GC-MS. (F) Volcano map displaying differential fecal metabolites identified using LC-MS. n = 7.