Research Paper Volume 16, Issue 15 pp 11513—11534

S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages

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Figure 3. The difference of tumor somatic mutation landscape between high- and low-expression groups of S100A9. (A) The distribution of the top 15 variants of mutated genes in the high- and low-expression groups of S100A9. The genetic alteration types were listed in the waterfall plots. The upper bar plots represent TMB. The numbers on the right of the bar plots indicated the mutation frequency of each gene. (B) Comparison of TMB between high- and low-expression groups of S100A9. (C) Differences in mismatch repair-relevant signatures between high- and low-expression groups of S100A9.