Research Paper Volume 16, Issue 12 pp 10512—10538

The crosstalk role of CDKN2A between tumor progression and cuproptosis resistance in colorectal cancer

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Figure 7. Regional annotation and expression of CDKN2A in spatial transcriptomic samples. (A) Malignancy scores on colorectal cancer spatial transcriptomic samples and on two types of tumor tissue stained with H&E. (B) Analysis of colorectal cancer spatial transcriptomic samples using the SpotSweeper R package. (C) Marker gene expression of all cell types in the tissues. Color depth represents the average expression level, and dot size represents the percentage of expressing cells. (D) Annotation of results from all sample regions, with different colors representing different regions. Sample numbers are listed above. (E) Expression of CDKN2A in colorectal cancer tissues. (F) Expression of CDKN2A in tumor regions and adjacent regions.