MATN4 as a target gene of HIF-1α promotes the proliferation and metastasis of osteosarcoma

Lu Zhang; Yujie Pan; Feng Pan; Songsong Huang; Fengyan Wang; Zhirui Zeng; Houping Chen; Xiaobin Tian

doi:doi:10.18632/aging.205941

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Research Paper Volume 16, Issue 12 pp 10462—10476

MATN4 as a target gene of HIF-1α promotes the proliferation and metastasis of osteosarcoma

Figure 7. Knockdown of HIF-1α reduced the promoting effects on migration and invasion of OS cell induced by MATN4 overexpression. (A) Transwell assays were used to detect the invasion ability in each group cells under hypoxia. (B) Wound healing assays were used to detect the invasion ability in each group cells under hypoxia. *, p <.05; **, p <.01.