Research Paper Volume 16, Issue 12 pp 10446—10461
Notoginsenoside R1 (NGR1) regulates the AGE-RAGE signaling pathway by inhibiting RUNX2 expression to accelerate ferroptosis in breast cancer cells
Figure 1. Prediction of potential target genes and signaling pathways of NGR1 in breast cancer. (A) The GSE205185 dataset was downloaded, and the R package “FactoMineR” and “factoextra” were used to perform principal component analysis on the two sets of samples. (B) Volcano map of differentially expressed genes in the GSE205185 dataset (C) Heat map of differentially expressed genes clustering in the GSE205185 dataset graph. (D) GSE205185 differential gene GO function enrichment analysis. (E) GSE205185 differential gene KEGG function enrichment analysis. (F) CTD database download NGR1 target gene and GSE205185 dataset plotting Wayne’s diagram. (G) Intersecting gene GO function enrichment analysis. (H) Intersecting gene KEGG functional enrichment analysis. (I) Intersecting genes PPI network diagrams.