Research Paper Volume 16, Issue 12 pp 10424—10434

The beneficial effects of Rosuvastatin in inhibiting inflammation in sepsis

class="figure-viewer-img"

Figure 6. Rosuvastatin inhibited LPS-induced production of proinflammatory cytokines in RAW 264.7 macrophages. Cells were stimulated with LPS (10 ng/mL) with or without Rosuvastatin (10 and 20 μM) for 24 hours. (A) Levels of TNF-α; (B) Levels of IL-6 (n=8, ***, P<0.005 vs. control; #, ##, P<0.05, 0.01 vs. LPS group).