Research Paper Volume 16, Issue 12 pp 10380—10401

Figure 4. Formononetin targeted genes related to metabolisms in tissue cells of prostate cancer. (A) GO enrichment analysis showed the biological roles of formononetin in metabolisms of tissue cells cluster of prostate cancer. (B) KEGG enrichment analysis showed the roles of formononetin’s targets in insulin resistance, cell adhesion, and necroptosis through the regulation of cell signaling pathways of tissue cells. Lower panel of each figure was the Circos plot to show the involvement of gene in each item. The size of bubble represented the number of gene. The color of bubble represented the significance of the biological processes and pathways.