Research Paper Volume 16, Issue 11 pp 9309—9333

Dietary sucrose determines the regulatory activity of lithium on gene expression and lifespan in Drosophila melanogaster

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Figure 2. sgg1FM7a are less responsive to lithium but highly responsive to dietary sucrose in regards of lifespan extension. Female sgg1FM7a flies were subjected to life-long interventions receiving either the 1%, 5% or 10% experimental diet supplemented with 0, 0.1 or 1 mM LiCl. (A) Dietary sucrose promoted longevity in sgg1FM7a. (B) Supplementing 0.1 or 1 mM LiCl to the 1% sucrose diet mildly promoted survival in sgg1FM7a. Survival curves were compared using the Log-Rank Mantel-Cox test (p ≤ 0.05).