Research Paper Volume 16, Issue 12 pp 10239—10251

MiR-33a-5p in stored red blood cells regulates genes of innate immune response and promotes inflammation

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Figure 1. (A) Correlation Heatmap of samples (GSE114990). (B) Heatmap of miRNA expression (GSE114990) (The abscissa represents days of storage). (C) The top 10 miRNAs that changed significantly with storage time were miR-720, miR-33a-5p, miR-198, miR-152, miR414, miR-32-5p, miR442, miR-144-3p, miR-142-5p, miR-590-5p. (D) The qRT–PCR to examine the top five miRNAs using qRT-PCR of the RBC samples we collected from the donors. All data are means ± SD; n = 3 (*P<0.05).