Research Paper Volume 16, Issue 11 pp 10033—10062

A new perspective: deciphering the aberrance and clinical implication of disulfidptosis signatures in clear cell renal cell carcinoma

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Figure 2. Establishment of two clusters of disulfide-related genes in ccRCC. (A) Consensus matrix of the samples in TCGA-KIRC for k = 2. (B) Cluster numbers are determined by the lowest proportion of ambiguous clusters. (C) Cumulative distribution function curves, k = 2–5. (D) Principal component plot based on disulfide-related genes. (E, F) Survival analysis of overall survival (left) and disease-free survival (right) of the two subtypes in the TCGA-KIRC dataset. (G) Expression profiles of disulfide-related genes in the two subtypes.