Research Paper Volume 16, Issue 11 pp 10016—10032
Landscape analysis of alternative splicing in kidney renal clear cell carcinoma and their clinical significance
Figure 7. Protective effect of FMR1 in KIRC. (A) The expressing level of FMR1 in KIRC and normal tissues. (B) The qRT-PCR detects FMR1 expression of paired paracancerous tissues and KIRC cancer tissues from Zhongnan Hospital. (C) Overexpression and knockdown efficiency in ACHN cells. (D) WB confirmed the overexpression and knockdown of FMR1 in ACHN cells. (E) MTT assay to investigate the proliferation of ACHN cells. (F) Clonogenic formation results from three independent experiments. (G) Transwell migration assay to investigate cell migration ability, scale bar = 100 μm. (H) Confirmed by statistical analysis. *p < 0.05, **p < 0.01, ***p < 0.001.