Research Paper Volume 16, Issue 11 pp 9972—9989
Disulfidptosis-related lncRNAs signature predicting prognosis and immunotherapy effect in lung adenocarcinoma
Figure 3. Construction of the disulfidptosis-related prognostic signature. (A) 10 DRG-lncRNAs significantly correlated with the survival prognosis of LUAD patients. (B) LASSO regression based on optimal parameter (lambda) construction model. (C) LASSO regression coefficient curve. (D) Multivariate Cox regression analysis of DRG-lncRNA with prognostic significance. (E, F) The Kaplan-Meier curve shows different OS and PFS between the low-risk and high-risk groups. (G) A heatmap shows the differential expression of DRG-lncRNAs in the high-risk and low-risk groups. (H) The risk curve of the training group is reordered by disulfidptosis related signature and the scatter plot of the sample survival overview. The green and red dots represent survival and death, respectively. (I) The risk curve of the test group is reordered by disulfidptosis related signature and the scatter plot of the sample survival overview. The green and red dots represent survival and death, respectively. Abbreviations: DRG-lncRNAs: disulfidptosis-related long non-coding RNAs; LUAD: lung adenocarcinoma; LASSO: least absolute shrinkage and selection operator; OS: overall survival; PFS: progression-free survival.