Research Paper Volume 16, Issue 11 pp 9813—9823

Targeting cGAS-STING signaling protects retinal ganglion cells from DNA damage-induced cell loss and promotes visual recovery in glaucoma

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Figure 5. Cisplatin induces lipid oxidation by causing mitochondrial dysfunction. (A, B) Maximal respiration was detected in RGC-5 cells when treated with cisplatin followed by C176. (C) Basal respiration was detected in RGC-5 cells when treated with cisplatin followed by C176. (D) ATP production was recorded in RGC-5 cells when treated with cisplatin followed by C176. (E, F) Mitochondrial membrane potential was determined in RGC-5 cells when treated with cisplatin followed by C176. *p<0.05.