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Figure 1.Bufotalin inhibits cell proliferation in GBM cells. (A) The molecular structure of bufotalin. (B, C) CCK-8 assay was used to determine the cell viability of U87 and U251 cells treated with bufotalin for 24 h and 48 h. (DG) Bufotalin suppressed U87 and U251 cells’ colony formation. The data are representative of three independent experiments and are presented as the mean ± SD. Significant differences compared with the control are indicated by *p < 0.05, **p < 0.01, and ***p < 0.001.
Figure 1 — Bufotalin enhances apoptosis and TMZ chemosensitivity of glioblastoma cells by promoting mitochondrial dysfunction via AKT signaling pathway | Aging