Research Paper Volume 16, Issue 11 pp 9547—9557

Neratinib stimulates senescence of mammary cancer cells by reducing the levels of SIRT1

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Figure 7. The effects of Neratinib in the expression of K382 acetylation of p53 (ac-K382) and p21. (A) Representative images of p53 (ac-K382) and p21 protein as measured by Western blot analysis (^, ^^, ^^^, P<0.05, 0.01, 0.005 vs. vehicle group).