Research Paper Volume 16, Issue 11 pp 9460—9469
High glucose enhances fibrosis in human annulus fibrosus cells by activating mTOR, PKCδ, and NF-κB signaling pathways
Figure 2. HG enhances fibrotic protein expression in HAFCs. HAFCs were treated with glucose (33 mM) or mannitol (33 mM) for 24 h, and the indicated mRNA (A) and protein (B) expression was examined by qPCR (n=5) and Western blot (n=3). (C) The densitometry analysis of (B) was quantified. * p < 0.05 versus the control group.