Figure 12. Assessment of biological function for AC002451.1. (A) RT-PCR validation following AC002451.1 knockdown in OSRC2 cells. (B) CCK-8 assay was performed to determine the proliferation ability of OSRC2 cells after AC002451.1 knockdown. (C) A wound healing assay was used to assess the migration ability of cells following AC002451.1 knockdown. (D, E) Transwell assay was used to assess the migration ability of cell lines following AC002451.1 knockdown. *p < 0.05, *p < 0.01, **p < 0.001, *p < 0.0001.