Leveraging pQTL-based Mendelian randomization to identify new treatment prospects for primary biliary cholangitis and primary sclerosing cholangitis

Lei Dai; Yunyan Ye; Joseph Mugaany; Zetong Hu; Jing Huang; Changjiang Lu

doi:doi:10.18632/aging.205867

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Research Paper Volume 16, Issue 10 pp 9228—9250

Leveraging pQTL-based Mendelian randomization to identify new treatment prospects for primary biliary cholangitis and primary sclerosing cholangitis

Figure 4. Funnel plots of Mendelian randomization (MR) analysis on PSC. (A) MR funnel plot for GSTO1 and PSC; (B) MR funnel plot for FCGR3A and PSC; (C) MR funnel plot for RNASET2 and PSC; (D) MR funnel plot for FCGR2A and PSC; (E) MR funnel plot for FCGR2B and PSC; (F) MR funnel plot for FCGR3B and PSC; (G) MR funnel plot for RNASE6 and PSC; (H) MR funnel plot for CTSB and PSC. Abbreviations: MR: Mendelian randomization; PSC: primary sclerosing cholangitis.